関連する実験動画

Updated: May 2, 2026

Protein Misfolding Cyclic Amplification of Prions
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Protein Misfolding Cyclic Amplification of Prions

Published on: November 7, 2012

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PrP(Sc) 複製によって種障壁を越えてインビトロでは,ユニークな感染性のプリオンを生成します

Joaquín Castilla1, Dennisse Gonzalez-Romero, Paula Saá

  • 1Department of Neurology, University of Texas Medical Branch, Galveston, TX 77555, USA.

Cell
|September 9, 2008
PubMed
まとめ

研究者らは,インビトロタンパク質の誤折りサイクル増幅 (PMCA) を使用して感染性のプリオンを作り出した. この研究は,プリオンタンパク質の誤折れが種間伝播と株の適応をいかに推進し,プリオン種のバリアに影響を与えるかを明らかにしています.

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