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Updated: May 6, 2026

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells
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Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells

Published on: March 9, 2012

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コロニン1Bはコルタクチンと対抗し,ラメリポディアのArp2/3を含むアクチン分岐を改造する

Liang Cai1, Alexander M Makhov, Dorothy A Schafer

  • 1Department of Cell and Developmental Biology, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7295, USA.

Cell
|September 9, 2008
PubMed
まとめ

コロニン1Bは,細胞移動に不可欠なプロセスであるラメリポディアのArp2/3-アクチンネットワークを分解します. この分解はコルタクチンによって阻害され,枝分かれしたアクチンダイナミクスを調節する重要なメカニズムを明らかにします.

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