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Updated: Jul 1, 2026

Quantification of three DNA Lesions by Mass Spectrometry and Assessment of Their Levels in Tissues of Mice Exposed to Ambient Fine Particulate Matter
12:15

Quantification of three DNA Lesions by Mass Spectrometry and Assessment of Their Levels in Tissues of Mice Exposed to Ambient Fine Particulate Matter

Published on: May 29, 2019

タンパク質結合は,過激派によるDNA損傷に大きく影響する.

Xiaohua Peng1, Ying Z Pigli, Phoebe A Rice

  • 1Department of Chemistry, The Johns Hopkins University, 3400 North Charles Street, Baltimore, Maryland 21218, USA.

Journal of the American Chemical Society
|September 10, 2008
PubMed
まとめ

タンパク質結合は,激素の反応性とDNAの鎖間クロスリンクを増加させることで,酸化性DNA損傷を著しく変化させます. この研究は,タンパク質が細胞環境におけるDNA損傷にどのように影響するかを明らかにしています.

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