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Updated: Jun 23, 2026

Analysis of Cell Cycle Position in Mammalian Cells
12:19

Analysis of Cell Cycle Position in Mammalian Cells

Published on: January 21, 2012

E2F1はβ-カテニンの転写を抑制し,pRBとCDK8の両方によって反抗する

Erick J Morris1, Jun-Yuan Ji, Fajun Yang

  • 1Laboratory of Molecular Oncology, Massachusetts General Hospital Cancer Center and Harvard Medical School, 13th Street, Building 149, Charlestown, Massachusetts 02129, USA.

Nature
|September 17, 2008
PubMed
まとめ

E2F1転写因子はベータ-カタニン/T細胞因子 (TCF) の活性を抑制し,アポトーシスを促進する. 結腸直腸腫瘍はRB1を維持し,CDK8を増幅してE2F1を抑制し,β-カタニン駆動の増殖を促進します.

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Identification of Cyclin-dependent Kinase 1 Specific Phosphorylation Sites by an In Vitro Kinase Assay12:26

Identification of Cyclin-dependent Kinase 1 Specific Phosphorylation Sites by an In Vitro Kinase Assay

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