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Updated: Jun 30, 2026

Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web
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複数のペプチド構成により,類似の結合親和性が生まれます:p53-MDM2の分子シミュレーション

Shubhra Ghosh Dastidar1, David P Lane, Chandra S Verma

  • 1Bioinformatics Institute (A-STAR), 30 Biopolis Street, #07-01 Matrix, Singapore 138671.

Journal of the American Chemical Society
|September 20, 2008
PubMed
まとめ

分子ダイナミクスシミュレーションは,ペプチド受容体結合親和性を正確に予測しました. 複合体内の2つの異なるペプチド構成は,エンタルピーまたはエントロピーによって誘発される,類似の結合強さを得ます.

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