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Updated: Jun 30, 2026

Dissecting Cell-Autonomous Function of Fragile X Mental Retardation Protein in an Auditory Circuit by In Ovo Electroporation
11:10

Dissecting Cell-Autonomous Function of Fragile X Mental Retardation Protein in an Auditory Circuit by In Ovo Electroporation

Published on: July 6, 2022

脆弱なX症候群タンパク質は,新しい4E-BPであるCYFIP1を通じて活動依存翻訳を抑制する

Ilaria Napoli1, Valentina Mercaldo, Pietro Pilo Boyl

  • 1Department of Biology, University Tor Vergata, Rome, Italy.

Cell
|September 23, 2008
PubMed
まとめ

脆弱なX型精神遅延タンパク質 (FMRP) は,シナプス性可塑性と脳の発達のための重要なメカニズムであるCYFIP1経由でニューロンにおける翻訳開始を阻害する. このプロセスは活動に依存し,シナプスのタンパク質合成を調節します.

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A Robust Polymerase Chain Reaction-based Assay for Quantifying Cytosine-guanine-guanine Trinucleotide Repeats in Fragile X Mental Retardation-1 Gene08:22

A Robust Polymerase Chain Reaction-based Assay for Quantifying Cytosine-guanine-guanine Trinucleotide Repeats in Fragile X Mental Retardation-1 Gene

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Analysis of Translation Initiation During Stress Conditions by Polysome Profiling10:59

Analysis of Translation Initiation During Stress Conditions by Polysome Profiling

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