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Updated: May 5, 2026

Proliferation and Differentiation of Murine Myeloid Precursor 32D/G-CSF-R Cells
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Proliferation and Differentiation of Murine Myeloid Precursor 32D/G-CSF-R Cells

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MLL白血病におけるグリコゲン合成キナーゼ3の維持と標的療法

Zhong Wang1, Kevin S Smith, Mark Murphy

  • 1Department of Pathology, Stanford University School of Medicine, Stanford, California 94305, USA.

Nature
|September 23, 2008
PubMed
まとめ

グリコゲン合成キナーゼ3 (GSK3) は,p27を不安定化することによって,驚くほどMLL白血病の進行を促します. GSK3を阻害することは,この攻撃的な白血病サブタイプに対する新しいがん薬戦略として有望であることが示されています.

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