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Updated: May 7, 2026

Visualization of DNA Repair Proteins Interaction by Immunofluorescence
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Sae2,Exo1とSgs1は,DNAの二重鎖断裂処理に協力しています

Eleni P Mimitou1, Lorraine S Symington

  • 1Department of Microbiology, Columbia University Medical Center, 701 West 168th Street, New York, New York 10032, USA.

Nature
|September 23, 2008
PubMed
まとめ

酵母菌のEXO1ヌクレアゼとSgs1ヘリカーゼは,DNAの二重鎖断裂 (DSB) を代替経路で処理する. Sae2は,初期のDSB処理に不可欠であり,Exo1とSgs1は,同類の再結合のための基板を生成するために,その後のステップで作用します.

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