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Updated: Jun 29, 2026

Intestinal Epithelial Regeneration in Response to Ionizing Irradiation
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セラミドバイオゲネシスは,C. elegansの生殖系における放射線誘発によるアポトーシスのために必要である

Xinzhu Deng1, Xianglei Yin, Richard Allan

  • 1Laboratory of Signal Transduction, Memorial Sloan-Kettering Cancer Center (MSKCC), New York, NY 10021, USA.

Science (New York, N.Y.)
|October 4, 2008
PubMed
まとめ

セラミド合成酵素の不活性化は,C. elegansの生殖細胞における放射線誘発によるアポトーシスをブロックする. ミトコンドリアでのセラミド生成は,CEP-1とEGL-1を含む並列経路を統合して,ストレス誘発の細胞死亡に不可欠です.

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