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Updated: Jun 29, 2026

Exploring Protein-Glycan Interactions: Advances in Nuclear Magnetic Resonance
10:07

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13C NMRのリラクゼーション分散からのリガンド結合のダイナミクスは,自然に豊富に存在する状態にある

John S Zintsmaster1, Brian D Wilson, Jeffrey W Peng

  • 1Department of Chemistry and Biochemistry, University of Notre Dame, 251 Nieuwland Science Hall, Notre Dame, Indiana 46556, USA.

Journal of the American Chemical Society
|October 7, 2008
PubMed
まとめ

Carr-Purcell-Meiboom-Gill (CPMG) 13Calpha NMRのリラクゼーション分散は,同位体ラベリングなしで受容体結合中のリガンドダイナミクスを測定する. この方法では,柔軟なリンガンド領域が明らかになり,複雑な形成と活動関係の理解に役立ちます.

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