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Updated: May 12, 2026

Assessment of Immunologically Relevant Dynamic Tertiary Structural Features of the HIV-1 V3 Loop Crown R2 Sequence by ab initio Folding
10:50

Assessment of Immunologically Relevant Dynamic Tertiary Structural Features of the HIV-1 V3 Loop Crown R2 Sequence by ab initio Folding

Published on: September 16, 2010

抗ウイルスAPOBEC3G触媒ドメインの結晶構造と機能的影響

Lauren G Holden1, Courtney Prochnow, Y Paul Chang

  • 1Molecular and Computational Biology, University of Southern California, Los Angeles, California 90089, USA.

Nature
|October 14, 2008
PubMed
まとめ

この研究では,ウイルスの複製を制限するタンパク質であるAPOBEC3G-CD2の高解像度の結晶構造が明らかになりました. この構造は,活性部位を明確にし,APOBECファミリーにおける基質特異性およびDNA結合のための重要な残基を特定します.

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