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Efficient Sampling of Genetically Encoded Biosensor Design Space Enabled with a Design of Experiments and Automation Workflow
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C. elegansの生殖線前駆体におけるグローバル転写抑制は,TAF-4の規制された結合によるものです

Tugba Guven-Ozkan1, Yuichi Nishi, Scott M Robertson

  • 1Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Cell
|October 16, 2008
PubMed
まとめ

OMA-1およびOMA-2タンパク質は,TAF-4と結合することで,C. elegansにおける初期の胚転写を抑制する. この調節はMBK-2キナーゼによって制御され,卵細胞の成熟から胚の発達への発達スイッチとして作用します.

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