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Updated: Jun 28, 2026

Mosaic Zebrafish Transgenesis for Functional Genomic Analysis of Candidate Cooperative Genes in Tumor Pathogenesis
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神経芽細胞腫におけるALKキナーゼの腫瘍性変異

Yuyan Chen1, Junko Takita, Young Lim Choi

  • 1Department of Pediatrics, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan.

Nature
|October 17, 2008
PubMed
まとめ

アナプラスティックリンパ腫キナーゼ (ALK) 変異は,進行性ニューロブラストーマでは一般的です. 変異したALKをターゲットにすることで,この治療不可能な小児がんに対する新しい治療戦略を提供することができます.

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