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関連する概念動画

Synthetic Biology02:55

Synthetic Biology

Synthetic biology is an interdisciplinary science that involves using principles from disciplines such as engineering, molecular biology, cell biology, and systems biology. It involves remodeling existing organisms from nature or constructing completely new synthetic organisms for applications such as protein or enzyme production, bioremediation, value-added macromolecule production, and the addition of desirable traits to crops, to name a few.
Golden rice
Golden rice is a genetically modified...
RNA-seq03:21

RNA-seq

RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while microarray-based...
Types of RNA01:20

Types of RNA

Three main types of RNA are involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). These RNAs perform diverse functions and can be broadly classified as protein-coding or non-coding RNA. Non-coding RNAs play important roles in regulating gene expression in response to developmental and environmental changes. Non-coding RNAs in prokaryotes can be manipulated to develop more effective antibacterial drugs for human or animal use.
RNA Performs Diverse...
Types of RNA01:23

Types of RNA

Overview
Three main types of RNA are involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). These RNAs perform diverse functions and can be broadly classified as protein-coding or non-coding RNA. Non-coding RNAs play important roles in the regulation of gene expression in response to developmental and environmental changes. Non-coding RNAs in prokaryotes can be manipulated to develop more effective antibacterial drugs for human or animal use.
RNA...
Types of RNA01:20

Types of RNA

Three main types of RNA are involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). These RNAs perform diverse functions and can be broadly classified as protein-coding or non-coding RNA. Non-coding RNAs play important roles in regulating gene expression in response to developmental and environmental changes. Non-coding RNAs in prokaryotes can be manipulated to develop more effective antibacterial drugs for human or animal use.
RNA Performs Diverse...
Types of RNA01:23

Types of RNA

Overview
Three main types of RNA are involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). These RNAs perform diverse functions and can be broadly classified as protein-coding or non-coding RNA. Non-coding RNAs play important roles in the regulation of gene expression in response to developmental and environmental changes. Non-coding RNAs in prokaryotes can be manipulated to develop more effective antibacterial drugs for human or animal use.
RNA...

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関連する実験動画

Updated: Jun 28, 2026

DNA-Tethered RNA Polymerase for Programmable In vitro Transcription and Molecular Computation
09:26

DNA-Tethered RNA Polymerase for Programmable In vitro Transcription and Molecular Computation

Published on: December 29, 2021

合成RNA装置による高次元の細胞情報処理

Maung Nyan Win1, Christina D Smolke

  • 1Division of Chemistry and Chemical Engineering, California Institute of Technology, 1200 East California Boulevard, MC 210-41, Pasadena, CA 91125, USA.

Science (New York, N.Y.)
|October 18, 2008
PubMed
まとめ

研究者は,複雑な細胞情報処理のためのRNA装置を設計した. これらのRNAロジックゲートは,遺伝子発現の正確な制御を可能にし,健康と医学における合成生物学の応用を進めています.

科学分野:

  • 合成生物学 合成生物学とは
  • 分子工学は分子工学である.
  • バイオテクノロジー バイオテクノロジー

背景:

  • 生物システム工学は,エネルギー,食品,環境,健康に関するソリューションを提供しています.
  • 細胞の情報処理は,生物システムの設計と操作の鍵です.

研究 の 目的:

  • 高度な細胞情報処理を行うことができるRNA装置を組み立てるための一般的なアプローチを開発する.
  • 細胞機能を制御するためのRNAベースの論理ゲートとシグナルフィルターを作成する.

主な方法:

  • 標準コンポーネントから組み立てられたRNAデバイス.
  • ロジックゲート (AND, NOR, NAND, OR) として機能するように設計されたデバイス.
  • 協力性を示す信号フィルターとしてのRNAデバイスを実証した.

主要な成果:

  • 機能的なRNAロジックゲートを成功裏に作成しました.
  • エンジニアリングされたRNAデバイスは,分子インプットを処理し,タンパク質アウトプットに転送することができます.
  • 計算を遺伝子発現と結びつける能力を実証した.

結論:

さらに関連する動画

A Multilayer Microfluidic Platform for the Conduction of Prolonged Cell-Free Gene Expression
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A Multilayer Microfluidic Platform for the Conduction of Prolonged Cell-Free Gene Expression

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Automated Robotic Liquid Handling Assembly of Modular DNA Devices
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Automated Robotic Liquid Handling Assembly of Modular DNA Devices

Published on: December 1, 2017

関連する実験動画

Last Updated: Jun 28, 2026

DNA-Tethered RNA Polymerase for Programmable In vitro Transcription and Molecular Computation
09:26

DNA-Tethered RNA Polymerase for Programmable In vitro Transcription and Molecular Computation

Published on: December 29, 2021

A Multilayer Microfluidic Platform for the Conduction of Prolonged Cell-Free Gene Expression
11:23

A Multilayer Microfluidic Platform for the Conduction of Prolonged Cell-Free Gene Expression

Published on: October 6, 2019

Automated Robotic Liquid Handling Assembly of Modular DNA Devices
11:22

Automated Robotic Liquid Handling Assembly of Modular DNA Devices

Published on: December 1, 2017

  • セルラーコンピューティングのための汎用的なRNAデバイスアセンブリアプローチを開発しました.
  • RNAデバイスは,細胞機能を制御し,合成生物学を進歩させるために強力なツールを提供します.
  • この作業は,様々な用途のために生物学的システムを設計し,探査する能力を高めます.