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Updated: Jun 28, 2026

Unraveling Entropic Rate Acceleration Induced by Solvent Dynamics in Membrane Enzymes
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Published on: January 16, 2016

ケンプ除去のための計算で設計された酵素の触媒機構と性能

Anastassia N Alexandrova1, Daniela Röthlisberger, David Baker

  • 1Sterling Chemistry Laboratory, Department of Chemistry, Yale University, New Haven, Connecticut 06520, USA.

Journal of the American Chemical Society
|November 4, 2008
PubMed
まとめ

研究者らは,5-ニトロベンジソクサゾールのケムプ除去のために人工酵素を設計した. コンピューティング・モデリングにより,3つの酵素 (KE07,KE10(V131N,KE15) の活性が予測され,さらなる酵素設計改善の洞察が提供されました.

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