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Updated: Jun 28, 2026

Utilizing Time-Resolved Protein-Induced Fluorescence Enhancement to Identify Stable Local Conformations One α-Synuclein Monomer at a Time
07:56

Utilizing Time-Resolved Protein-Induced Fluorescence Enhancement to Identify Stable Local Conformations One α-Synuclein Monomer at a Time

Published on: May 30, 2021

ナノディスクにおけるシトクロームP450 3A4からの基板解離に対するアロステリック効果は,アンサンブルおよび単分子光スペクトロスコーピーによって観察された

Abhinav Nath1, Peter K Koo, Elizabeth Rhoades

  • 1Department of Medicinal Chemistry, University of Washington, Seattle, Washington, USA.

Journal of the American Chemical Society
|November 5, 2008
PubMed
まとめ

単一分子光の研究は,エフェクタがサイトクロームP450 (CYP) 3A4酵素の運動にどのように影響するかを明らかにしています. エフェクターは,基板の放出を遅らせ,薬物の代謝を潜在的に強化することができます.

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