関連する実験動画

Updated: Jun 28, 2026

Chromatin Isolation by RNA Purification (ChIRP)
11:09

Chromatin Isolation by RNA Purification (ChIRP)

Published on: March 25, 2012

空気非コーディングRNAは,G9aをクロマチンにターゲティングすることで,伝記をエピジェネティックに静止させます

Takashi Nagano1, Jennifer A Mitchell, Lionel A Sanz

  • 1Laboratory of Chromatin and Gene Expression, Babraham Institute, Babraham Research Campus, Cambridge CB22 3AT, UK. takashi.nagano@bbsrc.ac.uk

Science (New York, N.Y.)
|November 8, 2008
PubMed
まとめ

空気のような大型非コーディングRNA (ncRNA) は,遺伝子をエピジェネティックに沈黙させます. 空気はG9a酵素を誘発し,マウスの胎盤におけるSlc22a3の遺伝子発現を静止させ,生後遺伝子静止のメカニズムを明らかにする.

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Epigenetic Regulation01:46

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Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.