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Updated: May 5, 2026

Radiolabeling and Quantification of Cellular Levels of Phosphoinositides by High Performance Liquid Chromatography-coupled Flow Scintillation
10:52

Radiolabeling and Quantification of Cellular Levels of Phosphoinositides by High Performance Liquid Chromatography-coupled Flow Scintillation

Published on: January 6, 2016

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IP-1:Fos/Junの支配的阻害体であり,その活動はリン酸化によって調節される

J Auwerx1, P Sassone-Corsi

  • 1Laboratoire de Génétique Moléculaire, Eucaryotes du CNRS, Faculté de Médecine, Strasbourg, France.

Cell
|March 8, 1991
PubMed
まとめ

新しい抑制タンパク質 (IP-1) は,DNA結合を防ぐことによって,転写因子AP-1の活性を阻害する. PKAによるリン酸化はIP-1を無活性化させ,遺伝子転写を調節するクロストークメカニズムを示唆する.

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