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Updated: May 18, 2026

Applying an Inducible Expression System to Study Interference of Bacterial Virulence Factors with Intracellular Signaling
08:51

Applying an Inducible Expression System to Study Interference of Bacterial Virulence Factors with Intracellular Signaling

Published on: June 25, 2015

膜タンパク質の誤翻訳と二成分系の活性化は,抗生物質による細胞死を引き起こす

Michael A Kohanski1, Daniel J Dwyer, Jamey Wierzbowski

  • 1Department of Biomedical Engineering, Center for BioDynamics, and Center for Advanced Biotechnology, Boston University, Boston, MA 02215, USA.

Cell
|November 18, 2008
PubMed
まとめ

アミノグリコシド抗生物質は,誤った折り畳まれた膜タンパク質に関連した酸化ストレスによって,細菌の細胞死を引き起こす. 封筒と酸化還元反応システムは,この細菌滅菌メカニズムの鍵です.

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