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Updated: Jun 27, 2026

Screening for Amyloid Aggregation by Semi-Denaturing Detergent-Agarose Gel Electrophoresis
10:03

Screening for Amyloid Aggregation by Semi-Denaturing Detergent-Agarose Gel Electrophoresis

Published on: July 16, 2008

アークティック (E22-->G) 変異がアミロイドβタンパク質の折りたたみに及ぼす影響: 離散分子ダイナミクス研究

A R Lam1, D B Teplow, H E Stanley

  • 1Center for Polymer Studies, Physics Department, Boston University, Boston, Massachusetts 02215, USA. arlam@buphy.bu.edu

Journal of the American Chemical Society
|December 5, 2008
PubMed
まとめ

アルツハイマー病はアミロイドβタンパク質 (Abeta) の折りたたみに関連しています. この研究は,北極の変異種を含むAbeta40とAbeta42が,どのように異なる折り畳みをし,集積経路に影響を与えるかを示すために,離散分子ダイナミクスを使用しています.

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