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圧力性潰瘍の治療:体系的なレビュー
Madhuri Reddy1, Sudeep S Gill, Sunila R Kalkar
1Department of Medicine, Hebrew Rehabilitation Center, 1200 Center St, Boston, MA 02131, USA. Madhuri.Reddy@hrca.harvard.edu
JAMA
|December 11, 2008
まとめ
圧力潰瘍の治療に関する証拠は限られている. あるレビューでは,標準的なケアよりも特定のサポート面,敷物,栄養補助食品,または補助療法に対する支持はほとんどなかった.
科学分野:
- 傷の癒し 傷の癒し
- クリニック・リサーチ 臨床研究
- 根拠に基づいた医学は,証拠に基づいた医療です.
背景:
- 圧迫性潰瘍は,多くの促進された治療法で重要な臨床的課題を代表しています.
- さまざまな圧力潰瘍治療の相対的な有効性は不明であり,包括的なレビューが必要である.
研究 の 目的:
- 圧迫性潰瘍の治療法を評価する公開されたランダム化対照試験 (RCT) を体系的にレビューする.
- 支持面,栄養補助食品,傷口包帯,補助療法の有効性に関する証拠を合成する.
主な方法:
- 英語で発表されたランダム化対照試験 (RCT) の系統的レビュー.
- 2008年8月23日までMEDLINE,EMBASE,CINAHLのデータベースで検索しました.
- 103のRCTから,方法論的特徴と結果を抽出しました.
主要な成果:
- 限られた証拠は,代替品よりも特定のサポート表面または敷き布団を支持しています.
- 1つの高品質の試験では,タンパク質サプリメントが長期介護の住民の傷の治癒を改善することを示しました.
- カルシウムアルギナート敷料は,デクストラノメールペーストと比較して治癒が改善され,他の敷料は優位性がありませんでした.
- 標準治療に対する生物学的薬剤と補助療法 (電流,超音波など) の効果は不明であった.
結論:
- 特定の支持面または敷料の日常的な使用を支持する堅実な証拠は不足しています.
- 定期的な栄養補給や補助療法では,標準的な圧迫性潰瘍治療と比較して,効果の証拠はほとんどありません.
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