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Updated: Jun 27, 2026

Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web
09:51

Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web

Published on: July 16, 2017

タンパク質の構成的移行:原子学的シミュレーションで探求されたキナーゼの閉塞機構

Anna Berteotti1, Andrea Cavalli, Davide Branduardi

  • 1Scuola Normale Superiore, Piazza dei Cavalieri, I-56126 Pisa, Italy.

Journal of the American Chemical Society
|December 11, 2008
PubMed
まとめ

原子模擬を用いて,サイクリン依存キナーゼ5 (CDK5) の大規模構造変化をシミュレートしました. 私たちの発見は,CDK5の2段階メカニズムを明らかにしています.

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Cooperative Allosteric Transitions01:58

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Cooperative Allosteric Transitions01:58

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