c-myc/IgHトランスロケーションにつながるc-mycの染色体破裂には,AIDが必要です

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Updated: May 3, 2026

Recombinant Retroviral Production and Infection of B Cells
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Recombinant Retroviral Production and Infection of B Cells

Published on: February 19, 2011

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Davide F Robbiani1, Anne Bothmer, Elsa Callen

  • 1Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.

Cell
|December 17, 2008
PubMed
まとめ

アクティベーション誘発型シチジンデアミナーゼ (AID) は,c-myc腫瘍遺伝子のDNA断裂を引き起こし,転位を引き起こす. この酵素は,抗体遺伝子変異だけでなく,腫瘍遺伝子の損傷に不可欠です.

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