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アミドの銅触媒によるN-アリレーションに関するメカニズム研究

Eric R Strieter1, Brijesh Bhayana, Stephen L Buchwald

  • 1Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA.

Journal of the American Chemical Society
|December 17, 2008
PubMed
まとめ

この研究は,アミドのN-アリレーションのための銅触媒化されたゴールドバーグ反応を詳細に説明しています. 発見は,活性銅種とアリルハリドの活性化メカニズムを制御するダイアミンリガンドの役割を強調しています.

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Acid-catalyzed hydrolysis:
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