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Updated: Jun 27, 2026

Detection of Toxin Translocation into the Host Cytosol by Surface Plasmon Resonance
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Published on: January 3, 2012

ディフテリア毒素によって触媒化されたNADの水解のための移行状態構造

Paul J Berti1, Steven R Blanke, Vern L Schramm

  • 1Contribution from the Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, and Department of Microbiology and Molecular Genetics, Harvard Medical School, 200 Longwood Avenue, Boston, Massachusetts 02115.

Journal of the American Chemical Society
|September 28, 2011
PubMed
まとめ

ダイフテリア毒素 (DTA) のNADの水解は,運動同位体効果 (KIEs) を使用して研究されました. これは,協調した,オキシカルベニウムイオンのような移行状態を明らかにし,DTAの触媒機構を明らかにしました.

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