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Updated: Apr 28, 2026

Quantification of γH2AX Foci in Response to Ionising Radiation
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WSTFは,H2A.XのDNA損傷反応を,新型のチロシンキナーゼ活性によって調節する

Andrew Xiao1, Haitao Li, David Shechter

  • 1Laboratory of Chromatin Biology, The Rockefeller University, New York, New York 10065, USA.

Nature
|December 19, 2008
PubMed
まとめ

ウィリアムズ・ブーレン症候群の転写因子 (WSTF) は新型のチロシンキナーゼ活性を持ち,H2A.Xをリン酸化してDNA損傷反応を調節し,真核細胞におけるクロマチンの改造を行う.

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