ボディマス指数と激しい身体活動と,男性における心不全のリスク
Satish Kenchaiah1, Howard D Sesso, J Michael Gaziano
1Physicians' Health Study, Brigham and Women's Hospital, Boston, MA 02215, USA. skenchaiah@rics.bwh.harvard.edu
Circulation
|December 24, 2008
まとめ
体重指数 (BMI) の上昇は,過剰体重の範囲であっても,心不全 (HF) のリスクを高めます. しかし,激しい運動は,男性におけるHFのリスクを大幅に低下させる.
科学分野:
- 心臓病学 心臓病学
- 公衆衛生は公衆衛生である.
- エピデミオロジー エピデミオロジー
背景:
- 肥満 (BMI ≥30 kg/m2) は,心不全 (HF) の既知の危険因子である.
- 肥満 (BMI 25~29.9 kg/m2) と身体活動がHFリスクに与える影響は,まだはっきりしていない.
研究 の 目的:
- 体質指数 (BMI) と激しい身体活動が心不全 (HF) の発生率に及ぼす独立した効果と組み合わせた効果を調査する.
主な方法:
- 医者の健康研究 (19822007) の21,094人の男性を対象とした前向きなコホート研究.
- BMIは継続的かつ断然的に評価され,激しい身体活動が二分化 (アクティブと非アクティブ) された.
- 混同因子調整とHFリスクを評価するために使用される多変量分析.
主要な成果:
- BMIの1kg/m2の上昇ごとに,HFのリスクが11%増加することが関連していました.
- 体重過多および肥満の男性は,痩せた男性と比較して,HFのリスクが著しく高かった (それぞれ49%および180%増加).
- 激しい運動はHFリスクの18%の減少と関連しており,BMIと運動の間の相互作用は観察されなかった.
結論:
- 体重過多/肥満前の範囲を含むBMIの上昇は,心不全のリスクの増加と関連しています.
- 強烈な身体活動は,心不全に対する保護効果を示しています.
- 健康的な体重と運動を促進する公衆衛生の取り組みは,心不全の発生率を軽減するために不可欠です.
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