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Updated: May 7, 2026

Lighting Up the Pathways to Caspase Activation Using Bimolecular Fluorescence Complementation
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Fas-FADD死亡領域複合体の構造は,受容体クラスタリングによるシグナル伝達を解析する

Fiona L Scott1, Boguslaw Stec, Cristina Pop

  • 1Program in Apoptosis and Cell Death Research, The Burnham Institute for Medical Research, La Jolla, California 92037, USA.

Nature
|January 2, 2009
PubMed
まとめ

Fas受容体とFADDの相互作用は,アポトーシスの決定的な死亡誘発信号複合体 (DISC) を形成します. 構造分析は,プログラムされた細胞死のための分子スイッチとして作用する規制Fas-FADD複合ブリッジを明らかにします.

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