Runx1は,内皮細胞から血液形成細胞への移行には必要ですが,その後は不要です

Michael J Chen1, Tomomasa Yokomizo, Brandon M Zeigler

  • 1Department of Biochemistry, Dartmouth Medical School, Hanover, New Hampshire 03755, USA.

Nature
|January 9, 2009
PubMed
まとめ

Runx1は,発達中のマウスの内皮細胞から血液形成性幹細胞 (HSC) を生成するのに不可欠です. その役割は血管系に不可欠ですが,HSCがVav1.1を発現すると必要ありません.

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