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Updated: Jun 26, 2026

Comparative Strategies for Ubiquitination Detection in Mammalian Cell Lysates Using SMAD2/SMURF2 as a Model
09:00

Comparative Strategies for Ubiquitination Detection in Mammalian Cell Lysates Using SMAD2/SMURF2 as a Model

Published on: April 17, 2026

FAM/USP9xは,TGFβシグナル伝達に不可欠なデウビキチン化酵素であり,Smad4のモノビキチン化を制御しています

Sirio Dupont1, Anant Mamidi, Michelangelo Cordenonsi

  • 1Department of Histology, Microbiology, and Medical Biotechnologies, University of Padua School of Medicine, viale Colombo 3, 35131 Padua, Italy.

Cell
|January 13, 2009
PubMed
まとめ

デウビキチナゼFAM (USP9x) は,Smad4モノビキチネーションを逆転させ,細胞応答の調節における重要なステップであるTGF-βシグナル伝達に不可欠である.

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Measuring Enzymatic Activity of Neurodevelopmental Disorder-Associated Deubiquitylating Enzymes via an In Vitro Ubiquitin Chain Cleavage Assay07:05

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