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Updated: May 2, 2026

Bead Aggregation Assays for the Characterization of Putative Cell Adhesion Molecules
08:15

Bead Aggregation Assays for the Characterization of Putative Cell Adhesion Molecules

Published on: October 17, 2014

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X関連カールマン症候群の候補遺伝子は,粘着分子に関連するタンパク質をコードする

R Legouis1, J P Hardelin, J Levilliers

  • 1Institut Pasteur Unité de Génétique Moléculaire Humaine (CNRS URA 1445), Paris, France.

Cell
|October 18, 1991
PubMed
まとめ

カールマン症候群 (Kallmann syndrome) は,ヒポゴナドトロピー性ヒポゴナディズムとアノスミアを引き起こす疾患で,胚性ニューロン移動に不可欠な欠陥遺伝子 (ADMLX) と関連しています. この研究では,患者の遺伝子中断を特定し,疾患におけるその役割を支持しました.

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Immunoglobulin-like cell adhesion molecules or Ig-CAMs are a versatile group of cell surface glycoproteins belonging to the immunoglobulin protein superfamily. Ig-CAMs possess the characteristic immunoglobulin protein domains and other domains such as the fibronectin type III domain. The Ig domains are glycosylated to varying degrees in different Ig-CAMs.
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