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Updated: May 13, 2026

Single-molecule Manipulation of G-quadruplexes by Magnetic Tweezers
08:28

Single-molecule Manipulation of G-quadruplexes by Magnetic Tweezers

Published on: September 19, 2017

オリゴーテル隔離器を介して複数のグアニジニウムイオンペンダントを運ぶ分子接着剤:デポリメリゼーションに対するマイクロチューブルの安定化

Kou Okuro1, Kazushi Kinbara, Kouhei Tsumoto

  • 1Department of Chemistry and Biotechnology, School of Engineering and Center for NanoBio Integration, The University of Tokyo, Tokyo, Japan.

Journal of the American Chemical Society
|January 17, 2009
PubMed
まとめ

新しいグアニジニウムで装飾されたデンドロンとペプチドオリゴーマーが,BSAやマイクロチューブルなどのタンパク質に効果的に結合します. これらの化合物はマイクロチューブルを安定させ,抗癌薬であるパクリタキセルに匹敵する潜在能力を示します.

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Visualizing Actin and Microtubule Coupling Dynamics In Vitro by Total Internal Reflection Fluorescence (TIRF) Microscopy08:44

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