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Updated: May 11, 2026

Juxtasomal Biocytin Labeling to Study the Structure-function Relationship of Individual Cortical Neurons
10:36

Juxtasomal Biocytin Labeling to Study the Structure-function Relationship of Individual Cortical Neurons

Published on: February 25, 2014

新皮質刺激結合のサブセルラー組織

Leopoldo Petreanu1, Tianyi Mao, Scott M Sternson

  • 1Janelia Farm Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia 20147, USA.

Nature
|January 20, 2009
PubMed
まとめ

研究者は,新しいチャネルロドプシン-2 (ChR2) 方法を使用して,マウスのバレル皮質ニューロンにシナプス入力をマッピングしました. 特定のインプットは,異なるデンドリット領域を標的とし,刺激性皮質回路の正確な組織を明らかにしました.

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Neuron Structure01:31

Neuron Structure

Overview
Neuron Structure01:30

Neuron Structure

Neurons are the main type of cell in the nervous system that generate and transmit electrochemical signals. They primarily communicate with each other using neurotransmitters at specific junctions called synapses. Neurons come in many shapes that often relate to their function, but most share three main structures: an axon and dendrites that extend out from a cell body.
Structure and Function of Neurons
The neuronal cell body—the soma— houses the nucleus and organelles vital to cellular...
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The Role of Ion Channels in Neuronal Computation

A postsynaptic neuron usually receives numerous impulses from several other presynaptic neurons. The axon hillock of the postsynaptic neuron integrates all these signals and determines the likelihood of firing an action potential.
Sometimes a single EPSP is strong enough to induce an action potential in the postsynaptic neuron. However, multiple presynaptic inputs must often create EPSPs around the same time for the postsynaptic neuron to be sufficiently depolarized to fire an action potential.
Neurons: The Cell Body and the Dendrites01:23

Neurons: The Cell Body and the Dendrites

A typical nerve cell comprises three main components: the cell body, dendrites, and the axon. The cell body, also known as the soma or perikaryon, serves as the central biosynthetic hub housing a nucleus surrounded by cytoplasm containing organelles commonly found in most cells. Notably, Nissl bodies, clusters of the rough endoplasmic reticulum and free ribosomes responsible for protein synthesis, are distinctive features of the neuronal cell body. As neurons age, aggregates of a brown pigment...
Neural Circuits01:25

Neural Circuits

Neural circuits and neuronal pools are two of the main structures found in the nervous system. Neural circuits are networks of neurons that work together to carry out a specific task or process. They consist of interconnected neurons and glial cells, which provide structural and metabolic support.
Neuronal pools are collections of nerve cells with similar functions and interact through chemical and electrical signals. These pools include both interneurons (the central neural circuit nodes that...
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Neuronal Communication

Neurons, the fundamental units of the brain and nervous system, communicate through complex electrochemical signals that underpin all cognitive and bodily functions. This communication is primarily facilitated by a process involving the generation and propagation of an action potential along the axon of the neuron. When the internal electrical charge of a neuron surpasses a certain threshold, an action potential is triggered. This rapid change in voltage travels swiftly along the axon to the...