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Updated: Jun 26, 2026

RNA Catalyst as a Reporter for Screening Drugs against RNA Editing in Trypanosomes
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ハンマーヘッドリボジームにおける一般酸触媒を検知する

Jason M Thomas1, David M Perrin

  • 1Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, B.C., Canada, V6T 1Z1.

Journal of the American Chemical Society
|January 22, 2009
PubMed
まとめ

二重金属カチオン (M(2+)) と特定のリボ酵素群は,ハンマーヘッドリボ酵素の一般的な酸触媒に不可欠です. この研究は,M2+) -コファクター協調がG8 2'-OH pKを低下させることを示し,それらの役割を明確にしています.

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