左心室の機能と運動能力
Jasmine Grewal1, Robert B McCully, Garvan C Kane
1Division of Cardiovascular Diseases, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA.
JAMA
|January 22, 2009
まとめ
左心室のダイアストリック機能障害は,静脈機能とは無関係に運動能力を著しく低下させる. この関連性は,高齢化や女性においてより顕著であり,腹動脈機能を強調しています.
科学分野:
- 心臓病学 心臓病学
- エコーカルディオグラフィー エコーカルディオグラフィー
- 運動生理学 運動生理学
背景:
- 運動能力に対する左心房機能の予測値に関するデータは限られている.
- この関係における年齢と性に関する差異を調査することは極めて重要です.
研究 の 目的:
- エコカルジオグラフィで決定された心臓機能が運動能力に与える影響を評価する.
- 性別と年齢がこれらの関連性を変化させるかどうかを判断する.
主な方法:
- 運動エコーカルディオグラフィー (ブルースプロトコル) を受けた2867人の患者の横断研究.
- 2Dとドップラー技術を用いて左心室のシストリックとダイアストリック機能を評価した.
- 缺血,低射出分数,または重大な弁疾患を有する患者を除外した.
主要な成果:
- ダイアストリック機能不全は,運動能力 (METs) と強く逆相関しています.
- 適度/重度の透析機能不全は, -1.30 METsの容量低下; -0.70 METsの軽度の機能不全.
- 通常のシストリック機能の変動は容量に影響を与えなかったが,充填圧の上昇 (E/e' ≥15) は容量を -0.41 METs 減少させた.
- 年齢,女性の性別,肥満 (BMI > 30) は,運動能力の独立した負の予測因子でした.
結論:
- 左心室のダイアストリック機能不全は,イシュケミアのない患者の運動能力の低下の独立した予測因子です.
- 結果は,運動能力の評価におけるダイアストリック機能評価の重要性を強調しています.
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