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異なるT細胞受容体信号がCD8+メモリとエフェクタルの発達を決定する

Emma Teixeiro1, Mark A Daniels, Sara E Hamilton

  • 1Experimental Transplantation Immunology, Department of Biomedicine, University Hospital-Basel, Hebelstrasse 20, 4031-Basel, Switzerland. teixeiropernase@missouri.edu

Science (New York, N.Y.)
|January 24, 2009
PubMed
まとめ

T細胞受容体ベータトランスメブラン領域 (betaTMD) の変異は,CD8+メモリT細胞の形成と機能を破壊する. これは,異なるT細胞受容体シグナル伝達経路が,効果因子対記憶T細胞の微分化を調節することを示唆しています.

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