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Updated: May 6, 2026

A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3
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規制されたT細胞抑制プログラムでは,トランスクリプション因子IRF4をT (H) 2反応の制御に利用しています

Ye Zheng1, Ashutosh Chaudhry, Arnold Kas

  • 1Howard Hughes Medical Institute, University of Washington, Seattle, Washington 98195, USA.

Nature
|February 3, 2009
PubMed
まとめ

調節性T細胞 (Treg) は,転写因子IRF4を使用して,T (H) 2の免疫反応を抑制する. Treg細胞におけるIRF4の喪失は,T(H) 2抑制を選択的に低下させ,自己免疫病理を引き起こす.

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