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Updated: May 7, 2026

Multi-target Parallel Processing Approach for Gene-to-structure Determination of the Influenza Polymerase PB2 Subunit
22:10

Multi-target Parallel Processing Approach for Gene-to-structure Determination of the Influenza Polymerase PB2 Subunit

Published on: June 28, 2013

鳥インフルエンザポリメラーゼPA(N) の結晶構造は,エンドヌクレアース活性部位を明らかにする

Puwei Yuan1, Mark Bartlam, Zhiyong Lou

  • 1National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.

Nature
|February 6, 2009
PubMed
まとめ

インフルエンザウイルスPAタンパク質 (PA(N)) のN末端ドメインは,ウイルスの複製に不可欠なエンドヌクレアース活性を持っています. この発見は,新しい抗インフルエンザ薬の開発の重要なターゲットとしてPA (((N) を特定しています.

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