2つの真菌ポリケチド合成酵素を含む遺伝子クラスタは,アスペルギルス・ニドゥランス (Aspergillus nidulans) のポリケチドであるアスペルフラノン (asperfuranone) の生合成経路をコードする

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Updated: Jun 25, 2026

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028
09:08

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028

Published on: January 13, 2017

Yi-Ming Chiang1, Edyta Szewczyk, Ashley D Davidson

  • 1Department of Pharmacology and Pharmaceutical Sciences, University of Southern California, School of Pharmacy, 1985 Zonal Avenue, Los Angeles, California 90089, USA.

Journal of the American Chemical Society
|February 10, 2009
PubMed
まとめ

アスペルギルス・ニドゥランス (Aspergillus nidulans) のゲノム採掘により,新しいポリケチドであるアスペルフュラノン (asperfuranone) を生成する神秘的な遺伝子群が発見された. この発見は,十分に研究された真菌で新しい天然製品を発見する可能性を強調しています.

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CRISPR-Cas9-Mediated Genome Editing in the Filamentous Ascomycete Huntiella omanensis

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