関連する実験動画
Updated: Jun 15, 2026

08:51
Microinjection for Transgenesis and Genome Editing in Threespine Sticklebacks
Published on: May 13, 2016
深いホモロジーと進化の新しさの起源
Neil Shubin1, Cliff Tabin, Sean Carroll
1Department of Organismal Biology and Anatomy, University of Chicago, 1027 East 57th Street, Chicago, Illinois 60637, USA. nshubin@uchicago.edu
Nature
|February 13, 2009
まとめ
新しい解剖学的構造は,既にあるものから進化し,de novoではない. 発達遺伝学と進化生物学は,古代の遺伝子制御回路の改変が,多様な動物の特徴の起源を支えていることを示しています.
科学分野:
- 進化的発達生物学 進化的発達生物学
- 発達遺伝学 発達遺伝学
- パレオントロジーの古生物学
背景:
- 新しい解剖学的構造の起源は,進化生物学における長年の疑問である.
- チャールズ・ダーウィンは,目,四肢,角などの複雑な構造の進化に魅了された.
研究 の 目的:
- 新しい解剖学的構造が新しいものから生じるか,あるいは既存の構造から進化するかを調べる.
- 重要な動物の特徴の発達の背後にある進化的メカニズムを理解する.
主な方法:
- 発達遺伝学の進歩を分析する.
- 考古学データの統合.
- 進化的発達生物学原理の適用について.
主要な成果:
- 動物の目,四足の四肢,甲虫の角のような重要な構造は,以前に存在していた構造から進化した.
- 古代の遺伝子制御回路の改変が主なメカニズムでした.
- 発達過程における深いホモロジーは,多様な構造の進化の基盤を提供する.
結論:
- 解剖学的構造は,新しいものから生まれず,既存の遺伝子と発達経路の改変によって進化する.
- メタゾーン間の深いホモロジーは,多様な構造の独立した進化を促進します.
関連する概念動画
The Evidence for Evolution
Genetic variations accumulating within populations over generations give rise to biological evolution. Evolutionary changes can result in the formation of novel varieties and entire new species. These changes are responsible for the diverse forms of life inhabiting the planet. The evidence for evolution suggests that all living organisms descended from common ancestors.The collection of fossils within sedimentary rocks give a record of common ancestry and often depicts the history of evolution.
Convergent Evolution
Evolution shapes the features of organisms over time, ensuring that they are suited for the environments in which they live. Sometimes, selection pressure leads to the rise of similar but unrelated adaptations in organisms with no recent common ancestors, a process known as convergent evolution.The structures that arise from convergent evolution are called analogous structures. They are similar in function even if they are dissimilar in structure. Further, structures can be analogous while also...
Evolutionary Relationships through Genome Comparisons
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
Synteny and Evolution
John H. Renwick first coined the term “synteny” in 1971, which refers to the genes present on the same chromosomes, even if they are not genetically linked. The species with common ancestry tend to show conserved syntenic regions. Therefore, the concept of synteny is nowadays used to describe the evolutionary relationship between species.
Around 80 million years ago, the human and mice lineages diverged from the common ancestor. During the course of evolution, the ancestral chromosome underwent...
Around 80 million years ago, the human and mice lineages diverged from the common ancestor. During the course of evolution, the ancestral chromosome underwent...
Gene Duplication and Divergence
The seminal work of Ohno in 1970 popularized the idea of gene duplication and divergence. DNA sequence comparison studies reveal that a large portion of the genes in bacteria, archaebacteria, and eukaryotes was generated by gene duplication and divergence, indicating its critical role in evolution.
The duplicated copies of the gene are called Paralogs. Paralogs with similar sequences and functions form a gene family. Across several species, a large number of gene families are characterized.
The duplicated copies of the gene are called Paralogs. Paralogs with similar sequences and functions form a gene family. Across several species, a large number of gene families are characterized.
Evolution of New Traits in Microbes
Microorganisms evolve rapidly due to their large population sizes and short generation times, often exhibiting measurable changes within days under laboratory conditions. Natural selection acts on standing genetic variation, enabling the retention and amplification of beneficial traits that confer fitness advantages in changing environments.Adaptive Pigment Regulation in RhodobacterIn Rhodobacter, a genus of purple non-sulfur bacteria, light-harvesting pigments such as bacteriochlorophyll and...

