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デンドリット細胞の受容体の特定により,死滅の感知と免疫の感知を結びつける

David Sancho1, Olivier P Joffre, Anna M Keller

  • 1Immunobiology Laboratory, London Research Institute, Lincoln's Inn Fields Laboratories, 44 Lincoln's Inn Fields, London WC2A 3PX, UK.

Nature
|February 17, 2009
PubMed
まとめ

死細胞は免疫反応を誘発する. CD8alpha+樹状細胞は,これらの細胞を感知するためにCLEC9Aを使用し,T細胞プライミングを開始します. この発見は,移植における免疫と癌の拒絶を理解するために不可欠です.

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