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Updated: Jun 25, 2026

Monitoring Equilibrium Changes in RNA Structure by 'Peroxidative' and 'Oxidative' Hydroxyl Radical Footprinting
13:41

Monitoring Equilibrium Changes in RNA Structure by 'Peroxidative' and 'Oxidative' Hydroxyl Radical Footprinting

Published on: October 17, 2011

リボヌクレオチド還元酵素中介物質Xのプロトン化酸素リガンドの識別

Muralidharan Shanmugam1, Peter E Doan, Nicholas S Lees

  • 1Department of Chemistry, Northwestern University, Evanston, Illinois 60208-3113, USA.

Journal of the American Chemical Society
|February 18, 2009
PubMed
まとめ

この研究では,リボヌクレオチド還元酵素の前駆体である中間Xは,端末aquaリガンドとmu-oxoブリッジを含んでいるが,mu-hydroxoブリッジは含まれていないことを確認した. これらの発見は,酵素の野生型と変異型の両方に適用されます.

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Expression and Purification of Nuclease-Free Oxygen Scavenger Protocatechuate 3,4-Dioxygenase10:14

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