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Updated: May 5, 2026

Quantification of γH2AX Foci in Response to Ionising Radiation
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H2AXのチロシン脱リン酸化は,アポプトシスと生存決定を調節する

Peter J Cook1, Bong Gun Ju, Francesca Telese

  • 1Howard Hughes Medical Institute School of Medicine, University of California, San Diego, California 92037, USA.

Nature
|February 24, 2009
PubMed
まとめ

タンパク質チロシンフォスファタゼEYAは,遺伝子毒性ストレス後のアポトーシスよりもDNA修復を促進します. ヒストンH2AX (Y142) を脱酸化し,哺乳類のオルガノゲネシス中に細胞の運命決定に影響を与えます.

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