Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Drug Products: Biologics, Biosimilars and Interchangeables01:28

Drug Products: Biologics, Biosimilars and Interchangeables

Biologics, derived from living sources such as humans, animals, or microorganisms, represent a significant category of pharmaceuticals. These complex molecules, developed through advanced biotechnological methods or purified from natural sources, include essential medical treatments like insulin and growth hormones. The complexity of biologics arises from their large molecular structures and the intricate processes required for their production, making them distinct from conventional...
Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
Modified-Release Drug Delivery Systems: Site-Targeted01:24

Modified-Release Drug Delivery Systems: Site-Targeted

Site-targeted drug delivery systems enhance therapeutic efficacy while minimizing systemic toxicity and treatment costs. Unlike conventional methods, these systems ensure precise drug delivery, improving bioavailability and reducing side effects. Targeted drug delivery is classified into three levels. First-order targeting directs drugs to the capillary beds of specific organs or tissues. Second-order targets specific cell types, such as tumor cells, using receptor-mediated interactions.
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Prescription, Nonprescription and Orphan Drugs01:02

Prescription, Nonprescription and Orphan Drugs

Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

The best words in the best order.

Nature·2011
Same author

Career decisions: Taking the plunge.

Nature·2011
Same author

Protein-protein interactions: Interactome under construction.

Nature·2010
Same author

Protein-protein interactions: Tools for the search.

Nature·2010
Same author

Protein-protein interactions: Real-time analysis.

Nature·2010
Same author

Biomedical science: Putting research into practice.

Nature·2010

関連する実験動画

Updated: Jun 25, 2026

Delivery of Therapeutic siRNA to the CNS Using Cationic and Anionic Liposomes
10:33

Delivery of Therapeutic siRNA to the CNS Using Cationic and Anionic Liposomes

Published on: July 23, 2016

RNAベースのセラピュティクス: 配達準備はできていますか?

Laura Bonetta

    Cell
    |February 26, 2009
    PubMed
    まとめ

    RNAベースの治療法は疾患の治療に有望ですが,標的組織への効果的な投与は依然として課題です. 現在進行中の臨床試験と動物実験は,これらの先進的な治療法の前向きな未来を示しています.

    科学分野:

    • バイオテクノロジー バイオテクノロジー
    • 分子医学は分子医学である.
    • 薬物の配送システムです.

    背景:

    • mRNAとsiRNAを含むRNAベースの治療法は,さまざまな病気の治療に重要な可能性を秘めています.
    • 特定の組織にRNA治療薬の効率的かつ標的を絞った投与は,臨床応用を阻害する重要な課題です.

    研究 の 目的:

    • RNAベースの治療法の現在の状況と将来の見通しを見直す.
    • RNA治療の組織特異的投与における課題と進歩を強調する.

    主な方法:

    • 現在の科学文献と臨床試験データのレビュー.
    • RNA配送メカニズムに焦点を当てた動物モデルでの臨床前研究の分析.

    主要な成果:

    • いくつかのRNAベースの治療戦略は,臨床試験を通して進歩しています.
    • 配送技術の進歩は,標的組織配分のための臨床前モデルの有望さを示しています.

    結論:

    • 配送のハードルにもかかわらず,RNAベースの療法の分野は急速に進歩しています.
    • 配送システムの将来の研究開発は,RNAベースの薬の治療の可能性を完全に実現するために不可欠です.

    さらに関連する動画

    Nanoparticle Delivery of an Oligonucleotide Payload in a Glioblastoma Multiforme Animal Model
    09:02

    Nanoparticle Delivery of an Oligonucleotide Payload in a Glioblastoma Multiforme Animal Model

    Published on: September 27, 2024

    Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts
    10:27

    Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts

    Published on: July 25, 2020

    関連する実験動画

    Last Updated: Jun 25, 2026

    Delivery of Therapeutic siRNA to the CNS Using Cationic and Anionic Liposomes
    10:33

    Delivery of Therapeutic siRNA to the CNS Using Cationic and Anionic Liposomes

    Published on: July 23, 2016

    Nanoparticle Delivery of an Oligonucleotide Payload in a Glioblastoma Multiforme Animal Model
    09:02

    Nanoparticle Delivery of an Oligonucleotide Payload in a Glioblastoma Multiforme Animal Model

    Published on: September 27, 2024

    Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts
    10:27

    Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts

    Published on: July 25, 2020