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Updated: Jun 19, 2026

Detection and Visualization of DNA Damage-induced Protein Complexes in Suspension Cell Cultures Using the Proximity Ligation Assay
13:10

Detection and Visualization of DNA Damage-induced Protein Complexes in Suspension Cell Cultures Using the Proximity Ligation Assay

Published on: June 9, 2017

細胞のプリオンタンパク質は,アミロイドベータオリゴーマーによるシナプス可塑性の低下を媒介する

Juha Laurén1, David A Gimbel, Haakon B Nygaard

  • 1Cellular Neuroscience, Neurodegeneration and Repair Program, Yale University School of Medicine, New Haven, Connecticut 06536, USA.

Nature
|February 27, 2009
PubMed
まとめ

アルツハイマー病は,アミロイドベータオリゴーマーが脳機能を損なうことを含む. 研究者は,このシナプス機能障害を媒介する重要な受容体として,細胞のプリオンタンパク質 (PrP(C)) を特定し,新しい治療標的を提供しました.

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