低所得の母親の糖尿病と胎内うつ病との関連
Katy Backes Kozhimannil1, Mark A Pereira, Bernard L Harlow
1Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, Massachusett, USA.
JAMA
|February 27, 2009
まとめ
妊娠中に糖尿病を患っている女性は,胎内うつ病のリスクがほぼ2倍に及ぶ. これには産後うつ病の新たな症例が含まれ,糖尿病と母親の精神的健康の間の重要な関連性を強調しています.
科学分野:
- 生殖器保健は,生殖器の健康についてです.
- エンドクリノロジー エンドクリノロジー
- 生後期の精神医学は,
背景:
- 産前うつ病は,新生児の10~12%が罹患しています.
- 糖尿病は妊娠の約9%を合併する.
- 現存する研究によると,糖尿病患者の間で重度のうつ病の罹患率が高いことが示されています.
研究 の 目的:
- 糖尿病 (妊娠期または妊娠期) と胎児期のうつ病との関連を調査する.
- 低所得の女性のコホートでこの関連性を調べる.
- 妊娠中および産後期の両方でうつ病を評価するために.
主な方法:
- ニュージャージー州メディケイドの行政請求データを活用した遡及的なコホート研究.
- 2004年7月から2006年9月の間に出産した女性11,024人を含む.
- 診断コードと処方箋クレームを使用して,出産の周りの定義された期間内に糖尿病とうつ病を評価しました.
主要な成果:
- 糖尿病の女性は,調整後,生後うつ病 (OR,1.85;95%CI,1.45-2.36) の確率をほぼ2倍にしました.
- 糖尿病の女性の15.2%がうつ病を経験し,糖尿病のない女性の8.5%と比較した.
- 糖尿病で産前うつ病の兆候がない女性は,産後うつ病の診断または抗うつ剤の使用の確率が高い (OR,1.69;95%CI,1.27-2.23).
結論:
- 妊娠前期と妊娠糖尿病は,分娩前期うつ病と独立して関連しています.
- 糖尿病は,産後うつ病の再発のリスクを高めます.
- この発見は,低所得の母集団にとって有意である.
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