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Updated: Jun 25, 2026

Assay Development for High-Throughput Drug Screening Against Mycobacteria
07:50

Assay Development for High-Throughput Drug Screening Against Mycobacteria

Published on: October 25, 2024

メロペネム・クラヴルナートは,薬剤耐性の高いMycobacterium tuberculosisに対して有効である

Jean-Emmanuel Hugonnet1, Lee W Tremblay, Helena I Boshoff

  • 1Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.

Science (New York, N.Y.)
|March 3, 2009
PubMed
まとめ

ベータ・ラクタム抗生物質は,BlaC酵素によるMycobacterium tuberculosisに対して失敗する. メロペネムとクラヴルナートを併用すると,薬剤耐性結核菌株に対して強力な活性を示します.

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