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Updated: Jun 25, 2026

Isolation and Chemical Characterization of Lipid A from Gram-negative Bacteria
12:57

Isolation and Chemical Characterization of Lipid A from Gram-negative Bacteria

Published on: September 16, 2013

TLR4-MD-2複合体によるリポポリサッカリド認識の構造的基礎

Beom Seok Park1, Dong Hyun Song, Ho Min Kim

  • 1Department of Chemistry, KAIST, Daejeon, 305-701, Korea.

Nature
|March 3, 2009
PubMed
まとめ

Toll型受容体4 (TLR4) -ミエロイド分化因子2 (MD-2) -リポポリサッカリド (LPS) 複合体の結晶構造は,LPSが生まれつきの免疫を活性化する方法を示しています. LPSの結合は,細菌の防御に不可欠な受容体マルチメリゼーションを誘発する.

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