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Quantitative Analysis of Cell Edge Dynamics during Cell Spreading
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N-WASPの交換率は,ARP2/3複合体依存のアクチンベースの運動性の範囲を制限する

Ina Weisswange1, Timothy P Newsome, Sibylle Schleich

  • 1Cell Motility Laboratory, Cancer Research UK, London Research Institute, 44 Lincoln's Inn Fields, London WC2A 3PX, UK.

Nature
|March 6, 2009
PubMed
まとめ

病原体のアクチンベースの運動性は,局所的なシグナル伝達に依存しています. ニューロンのウィスコット・オールドリッチ症候群タンパク質 (N-WASP) の動態を研究し,その交換率がアクチンポリメリゼーションを調節することによってウイルスの動きを制御することを発見しました.

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