ヘパトスプレニック・スキストソミアシスの心肺症状
Monica Lapa1, Bruno Dias, Carlos Jardim
1Pulmonary Hypertension Group, Pulmonary Department, Heart Institute, University of Sao Paulo Medical School, Sao Paulo, Brazil.
Circulation
|March 11, 2009
まとめ
ヘパトスフェニックスキストソミアシスは,世界中で肺高血圧の一般的な原因です. エコーカルディオグラフィは有用なスクリーニングツールですが,診断には右心臓のキャセテリゼーションが必要です.
科学分野:
- トロピカル・メディシン (熱帯医学)
- 心臓病学 心臓病学
- 感染症 感染症は感染症です.
背景:
- スキストソミアシスは,世界全体で2億人以上が罹患しています.
- 肺高血圧は,スキストソミアシスの合併症であり,特にヘパトスプレニック形態は知られている.
- この特定の患者群における肺高血圧の有病率は,さらなる調査を必要とする.
研究 の 目的:
- ヘパトスプレニックスキストソミアシス患者における肺高血圧の有病率を決定する.
主な方法:
- 肺高血圧 (シストリック肺動脈圧>40mmHg) のスクリーニングにエコーカルディオグラフィを使用しました.
- 値が上昇した患者は,侵襲的な血液動力学的評価のために右心臓のキャセテリゼーションを受けた.
- 収縮性肺動脈圧の上昇と肺高血圧の確認の有病率を計算した.
主要な成果:
- エコーカルディオグラフィーは,患者の18.5%でシストリック肺動脈の圧力が上昇したことを明らかにしました.
- 患者の7.7%で右心経キャセテリゼーションにより肺高血圧が確認されました.
- 前毛細血管 (動脈) 肺高血圧は,研究コーホートの4.6%で診断されました.
結論:
- エコーカルディオグラフィは,スキストソミアシス患者における肺高血圧の有効なスクリーニングツールとして機能します.
- 侵襲的な血液動力学的モニタリングは,正確な診断のために不可欠です.
- ヘパトスプレニックスキストソミアシスは,肺高血圧の世界的な負担に大きく寄与しており,標的治療へのさらなる研究を正当化しています.
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